Table S4: Occurrence rate of genes within significant clusters in the spc operon Group rplN rplX rplE rpsN rpsH rplF rplR rpsE rpmD rplO SecY rpmJ Acidobacteria 100.0% 100.0% 100.0% 100.0% 100.0% 100.0% 100.0% 100.0% 0.0% 0.0% 100.0% 100.0% Actinobacteria 100.0% 100.0% 100.0% 79.4% 100.0% 100.0% 100.0% 100.0% 88.2% 0.0% 100.0% 61.8% Alphaproteobacteria 100.0% 100.0% 100.0% 100.0% 100.0% 98.1% 86.5% 100.0% 69.2% 0.0% 100.0% 0.0% Betaproteobacteria 100.0% 100.0% 100.0% 100.0% 100.0% 100.0% 100.0% 100.0% 100.0% 94.4% 100.0% 83.3% Deltaproteobacteria 100.0% 92.9% 100.0% 85.7% 100.0% 92.9% 100.0% 100.0% 50.0% 0.0% 100.0% 64.3% Epsilonproteobacteria 100.0% 100.0% 100.0% 72.7% 100.0% 100.0% 9.1% 100.0% 0.0% 0.0% 100.0% 63.6% Gammaproteobacteria 99.0% 100.0% 100.0% 100.0% 100.0% 100.0% 100.0% 100.0% 90.8% 100.0% 100.0% 76.5% Aquificae 100.0% 100.0% 100.0% 100.0% 100.0% 100.0% 100.0% 100.0% 0.0% 0.0% 0.0% 0.0% Bacteroidetes/Chlorobi 100.0% 100.0% 100.0% 100.0% 100.0% 100.0% 100.0% 100.0% 90.0% 10.0% 100.0% 40.0% Chlamydiae/Verrucomicrobia 100.0% 63.6% 100.0% 0.0% 100.0% 100.0% 100.0% 100.0% 0.0% 0.0% 100.0% 0.0% Chloroflexi 100.0% 100.0% 100.0% 100.0% 100.0% 100.0% 100.0% 100.0% 0.0% 0.0% 100.0% 100.0% Cyanobacteria 100.0% 100.0% 100.0% 36.8% 100.0% 100.0% 100.0% 100.0% 0.0% 0.0% 94.7% 84.2% Deinococcus-Thermus 75.0% 75.0% 75.0% 50.0% 100.0% 100.0% 100.0% 100.0% 50.0% 0.0% 100.0% 100.0% Firmicutes 100.0% 100.0% 100.0% 90.5% 100.0% 100.0% 98.9% 98.9% 66.3% 3.2% 98.9% 86.3% Fusobacteria 100.0% 0.0% 100.0% 100.0% 100.0% 100.0% 100.0% 100.0% 100.0% 0.0% 100.0% 0.0% Planctomycetes 100.0% 100.0% 100.0% 100.0% 100.0% 100.0% 100.0% 100.0% 0.0% 0.0% 100.0% 0.0% Spirochaetes 100.0% 100.0% 100.0% 55.6% 100.0% 100.0% 100.0% 100.0% 33.3% 0.0% 100.0% 88.9% Thermotogae 100.0% 100.0% 100.0% 100.0% 100.0% 100.0% 100.0% 100.0% 100.0% 0.0% 100.0% 100.0% Total 99.5% 98.2% 99.8% 87.5% 100.0% 99.5% 95.5% 99.8% 69.2% 34.0% 99.2% 65.0%